Top Sites>Sterigenics | Global Leader in Sterilization Solution

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# Sterigenics \- The Global Leader in Contract Sterilization Services

> Sterigenics is a global leader in sterilization solutions in the medical device, pharmaceutical, advanced applications, commercial, and food industries\.

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## Pages
- [Resources](https://sterigenics.com/resources/)
- [Whitepapers \& Case Studies](https://sterigenics.com/resources/white-paper/)
- [Quality](https://sterigenics.com/about-us/quality/)
- [Home](https://sterigenics.com/)
- [Site Map](https://sterigenics.com/site-map/)

## Posts
- [Sterigenics Celebrates Opening of New X\-Ray Sterilization Facility in Southeast United States](https://sterigenics.com/new_x-ray-sterilization-facility-southeast-united-states/)
- [Sterigenics Announces New X\-ray Sterilization Capabilities  in the Southeast United States](https://sterigenics.com/sterigenics-announces-new-x-ray-sterilization-capabilities-in-the-southeast-united-states/)
- [Nordion, Westinghouse, and PSEG Reach Key Milestones to Launch First\-Ever Production of Cobalt\-60 in U\.S\. Pressurized Water Reactors](https://sterigenics.com/nordion-westinghouse-and-pseg-reach-key-milestones-to-launch-first-ever-production-of-cobalt-60-in-u-s-pressurized-water-reactors/)

## Technologies
- [Gamma Sterilization](https://sterigenics.com/technologies/gamma-irradiation/): Using pure energy, Gamma irradiation deeply penetrates products and their packaging to effectively kill microorganisms\. Perfect for high\-density products such as pre\-filled syringes, medical devices, and orthopedic products\.
- [X\-Ray Sterilization](https://sterigenics.com/technologies/x-ray-sterilization/): X\-Ray irradiation uses ionizing energy from high\-powered electron beam accelerators, with its high penetration, x\-ray supports the sterilization of a wide variety of products\.
- [Ethylene Oxide Sterilization](https://sterigenics.com/technologies/ethylene-oxide/): Ethylene Oxide Sterilization \(EO or ETO Sterilization\) is achieved all in one chamber, effectively permeating packaging and minimizing residuals\. 
- [Electron Beam Sterilization](https://sterigenics.com/technologies/electron-beam/): With its low penetration and high\-dosage rates, Electron beam, or E\-Beam sterilization is best suited for use on low\-density, uniformly packaged products\. 
- [Noxilizer \(NO\<sub\>2\</sub\> Sterilizer\)](https://sterigenics.com/technologies/noxilizer-no2/): Nitrogen Dioxide \(NO\<sub\>2\</sub\>\)\-based sterilization offers ultra\-low temperature, minimal pressure requirements, no cytotoxic residuals, and fast cycle times\. 

## Industries
- [Pharmaceutical \& Bioprocessing](https://sterigenics.com/industries/pharmaceutical/): Clinics and physicians rely on manufacturers to ensure drug efficacy of active pharmaceutical ingredients \(APIs\) and sterility assurance across the supply chain—for the health and safety of their patients\.
- [Medical Device](https://sterigenics.com/industries/medical-device/): Medical devices are complex, so choice of industrial sterilization technology must take into consideration the device’s design, material, product packaging, and final packaging\.
- [Restoration \& Salvage](https://sterigenics.com/industries/food-commercial-products/restoration/)
- [Cosmetic Products \& Packaging](https://sterigenics.com/industries/food-commercial-products/cosmetics/)
- [Food Safety \& Commercial Products](https://sterigenics.com/industries/food-commercial-products/): Radiation technologies are proven, effective solutions to reduce microbial contamination while maintaining product quality and integrity\.

## Expert Bio
- [Ashley \(Ash\) Hobson](https://sterigenics.com/expert-bio/ashley-hobson/)
- [David Tran](https://sterigenics.com/expert-bio/david-tran/)
- [Thomas Quanten](https://sterigenics.com/expert-bio/thomas-quanten/)
- [John Schlecht](https://sterigenics.com/expert-bio/john-schlecht/)
- [Aaron DeMent](https://sterigenics.com/expert-bio/aaron-dement/)

## Location
- [Haw River, North Carolina, USA \- X\-Ray](https://sterigenics.com/location/haw-river-north-carolina-usa-x-ray/)
- [Corona, California, USA](https://sterigenics.com/location/corona/)
- [Hidalgo, México \- Gamma](https://sterigenics.com/location/hidalgo-mexico-gamma/)
- [Alajuela, Costa Rica](https://sterigenics.com/location/alajuela-costa-rica/)
- [Jarinu, Brazil](https://sterigenics.com/location/jarinu/)

## Event
- [INTERPHEX](https://sterigenics.com/event/interphex/): Sterigenics is happy to announce it will be exhibiting with Nelson Labs and Regulatory Compliance Associates \(RCA\) at the INTERPHEX conference in New York City, April 21\-23, 2026\. 

## Brochures
- [Sterigenics GPS Global Processing Status®: Customer Portal](https://sterigenics.com/brochure/sterigenics-gps-global-processing-status-customer-portal/)
- [Stored Energy Device Safety Assessment for Ethylene Oxide Sterilization](https://sterigenics.com/brochure/stored-energy-device-safety-assessment-for-ethylene-oxide-sterilization/)
- [Electron Beam](https://sterigenics.com/brochure/electron-beam/)
- [Ethylene Oxide](https://sterigenics.com/brochure/ethylene-oxide/)
- [ExCell\<sup\>®\</sup\> Irradiator](https://sterigenics.com/brochure/nothing-can-equal-theexcell-irradiator/)

## Published Articles
- [Preserve \& Protect: Ortho Device Packaging \& Sterilization](https://sterigenics.com/published-article/preserve-protect-ortho-device-packaging-sterilization/): Packaging and sterilization play a crucial role in the safety, performance, and regulatory compliance of orthopedic devices\. As implants and instruments become more complex, the means used to protect and sterilize them must evolve in tandem\.
- [Impact of Changing Medical Device Sterilization Methods](https://sterigenics.com/published-article/impact-of-changing-medical-device-sterilization-methods/): Experts guide medical device manufacturers through the intricate process of transitioning from one sterilization method to another\.
- [Nitrogen dioxide sterilization of a set of five ophthalmic active pharmaceutical ingredients: Impact on impurity profile and content](https://sterigenics.com/published-article/nitrogen-dioxide-sterilization-of-a-set-of-five-ophthalmic-active-pharmaceutical-ingredients-impact-on-impurity-profile-and-content/): Literature about sterilization of pharmaceutical substances is limited\. The aim of this study was to evaluate the effect of nitrogen dioxide \(NO2\) sterilization, a new emerging technology, on five different ophthalmic active pharmaceutical ingredients\.\.\.
- [Darlington Nuclear’s Newly Refurbished Unit 1 now Producing life\-saving Cobalt\-60 Isotopes](https://sterigenics.com/published-article/darlington-nuclears-newly-refurbished-unit-1-now-producing-life-saving-cobalt-60-isotopes/): The recently refurbished Unit 1 reactor at OPG’s Darlington Nuclear Generating Station is now producing critical life\-saving Cobalt\-60 isotopes for the world\.\.\.
- [Statistical analysis of spikes in bioburden](https://sterigenics.com/published-article/statistical-analysis-of-spikes-in-bioburden-elsevier-journal-of-radiation-physics-and-chemistry-2012/)

## On Demand Webinars
- [Optimizing Ethylene Oxide Sterilization: Sustainable Solutions for Pharmaceutical Packaging and Drug Delivery Devices](https://sterigenics.com/webinar/optimizing-ethylene-oxide-sterilization-sustainable-solutions-for-pharmaceutical-packaging-drug-delivery-devices/): Ethylene oxide \(EO\) remains the sterilization method of choice for approximately 50% of all single\-use medical devices worldwide\.\.\.
- [Navigating the Decision Flow: Changing Sterilization\<br\>Modalities for Medical Devices](https://sterigenics.com/webinar/navigating-the-decision-flow-changing-sterilizationmodalities-for-medical-devices/): As global regulatory pressures tighten and supply chain challenges increase, medical device manufacturers are increasingly considering changes to sterilization modalities—whether due to material compatibility, environmental impact, or technology accessibility\.\.\.\.
- [Radiation Sterilization: What do product characteristics\<br\>tell you about the type and source of radiation to use?](https://sterigenics.com/webinar/what-do-product-characteristicstell-you-about-the-type-and-source-of-radiation-to-use/): Since the installation of the first irradiators for the sterilization of single\-use healthcare products in the 1960’s, this application of ionizing radiation has evolved into\.\.\.
- [Validating Ethylene Oxide Sterilization Processes\<br\>for Compliance and Reliability](https://sterigenics.com/webinar/validating-ethylene-oxide-sterilization-processes-compliance-reliability/): The validation of ethylene oxide \(EO\) sterilization processes for medical devices is a critical component in ensuring device safety and efficacy\.\.\.
- [Benefits of Parametric Release\<br\>for EO Sterilization](https://sterigenics.com/webinar/benefits-of-parametric-releasefor-eo-sterilization/): Join us for an informative webinar that reviews the benefits of parametric release and the general steps that Sterigenics follows to establish the Parametric Release specifications in accordance with\.\.\.

## Video Gallery
- [Sterigenics and MedAccred Sterilization Accreditation](https://sterigenics.com/video/sterigenics-and-medaccred-sterilization-accreditation/): Aaron DeMent, Vice President of Sterilization Technologies at Sterigenics shares his perspective on the value of MedAccred Sterilization Accreditation to Sterigenics and to the medical device industry\.
- [Radiation Sterilization – What is the ideal dose range specification for my product?](https://sterigenics.com/video/radiation-sterilization-what-is-the-ideal-dose-range-specification-for-my-product/): Methods for substantiation of the sterilization dose and establishment of the maximum sterilization dose\.
- [Is Your Product Sterile or Sterilized? Comparison between Aseptic Assembly and Terminal Sterilization\.](https://sterigenics.com/video/is-your-product-sterile-or-sterilized/): Screening approach of methods suitable for Pharma product\.

## Industry Insights
- [The Role of Irradiation in the Production of Bioinputs for Sustainable Agriculture](https://sterigenics.com/industry-insights/the-role-of-irradiation-in-the-production-of-bioinputs-for-sustainable-agriculture/): Bioinputs are agro\-industrial products or processes derived from living organisms or their byproducts\. These include microorganisms, enzymes, plant extracts, and other biological materials\.\.\.
- [The Effect of Gamma and Ethylene Oxide Sterilization on a Selection of Active Pharmaceutical Products \(APIs\) for Ophthalmics](https://sterigenics.com/industry-insights/the-effect-of-gamma-and-ethylene-oxide-sterilization-on-a-selection-of-active-pharmaceutical-products-apis-for-ophthalmics/): Increasingly stringent product sterility requirements and guidance are being included in global regulatory documents issued by regulatory bodies\.\.\.
- [To Use or Not to Use a Developmental Chamber for Ethylene Oxide Validation](https://sterigenics.com/industry-insights/to-use-or-not-to-use-a-developmental-chamber-for-ethylene-oxide-validation/): A developmental chamber is usually smaller than a production chamber and used to perform studies to support Ethylene Oxide \(EO\) validation\. There are several pros of using developmental chamber; for example, smaller sample sizes can lower laboratory testing costs\. In this Industry Insight, we offer Project Management and Quality Assurance personnel within the medical device, pharmaceutical, commercial and food industries the pros and cons of using a developmental chamber for Process Definition performed as part of a validation, in adherence with ISO 11135:2014, using the Overkill Approach\.
- [Comparing Terminal Sterilization and Aseptic Processing of Pharmaceutical Products](https://sterigenics.com/industry-insights/comparing-terminal-sterilization-and-aseptic-processing-of-pharmaceutical-products/): The purpose of sterilization is to provide to the patient an efficient drug product that can be used with the highest safety level\. Terminal sterilization\.\.\.

## White Paper
- [Auto\-Injectors: Proving the Effectiveness of Advanced Surface Sterilization](https://sterigenics.com/white-paper/auto-injectors-proving-the-effectiveness-of-advanced-surface-sterilization/): Sterigenics empowering pharmaceutical innovators to confidently deliver sterile, patient ready auto injectors, by assisting them in solving complex design and stability challenges with a customized ethylene oxide \(EO\) surface sterilization solution\.
- [Material Consideration Radiation Processing](https://sterigenics.com/white-paper/material-consideration-radiation-processing/): Each polymer reacts differently to ionizing radiation\. Thus, it is important to verify that the maximum administered dose will not have a detrimental effect on the product’s function or the patient’s safety over the product’s intended shelf life\.
- [Pros, Cons and Considerations of Using a Developmental Chamber During Ethylene Oxide Validation](https://sterigenics.com/white-paper/pros-cons-and-considerations-of-usinga-developmental-chamber-during-ethylene-oxide-validation/): A developmental chamber is usually smaller than a production chamber and used to perform studies to support Ethylene Oxide validation\. This white paper discusses use of a developmental chamber for Process Definition\.\.\.

- [Sterilization Dose Audits – The “Why” and the “How”](https://sterigenics.com/white-paper/sterilization-dose-audits-the-why-and-the-how/): In the medical device industry, sterilization processing is performed to obtain a Sterility Assurance Level \(SAL\) as required by regulatory authorities to designate the treated product as “sterile”\. When SAL is established …
- [How to Evaluate a New Product Against an Existing Product in a Validated Ethylene Oxide Process](https://sterigenics.com/white-paper/how-to-evaluate-a-new-product-against-an-existing-product-in-a-validated-ethylene-oxide-process/): As defined in Section 12 of ISO 11135:2014, a new or modified \(“candidate”\) product can be added to a validated Ethylene Oxide \(EO\) sterilization process

## Categories
- [Uncategorized](https://sterigenics.com/category/uncategorized/)

## Brochure Category
- [Radiation](https://sterigenics.com/brochure-category/radiation/)
- [Ethylene Oxide](https://sterigenics.com/brochure-category/eo/)
- [Other](https://sterigenics.com/brochure-category/other/)

## Published Articles Category
- [Radiation](https://sterigenics.com/published-articles-category/radiation/)
- [Ethylene Oxide](https://sterigenics.com/published-articles-category/ethylene-oxide/)

## Event Category
- [Tradeshow](https://sterigenics.com/event-category/tradeshow/)

## Location Region
- [North America](https://sterigenics.com/location-region/north-america/)
- [Europe](https://sterigenics.com/location-region/europe/)
- [Asia](https://sterigenics.com/location-region/asia/)
- [South America](https://sterigenics.com/location-region/south-america/)
- [Central America](https://sterigenics.com/location-region/central-america/)

## Location Technology
- [Gamma Irradiation](https://sterigenics.com/location-technology/gamma-irradiation/)
- [Ethylene Oxide](https://sterigenics.com/location-technology/ethylene-oxide/)
- [Electron Beam](https://sterigenics.com/location-technology/electron-beam/)
- [X\-Ray](https://sterigenics.com/location-technology/x-ray/)

## Webinar Category
- [Gamma Radiation](https://sterigenics.com/webinar-category/radiation/)
- [Ethylene Oxide](https://sterigenics.com/webinar-category/ethylene-oxide/)
- [Sterilization Overview](https://sterigenics.com/webinar-category/sterilization-overview/)
- [X\-Ray](https://sterigenics.com/webinar-category/x-ray/)
- [Electron Beam](https://sterigenics.com/webinar-category/electron-beam/)

## White Paper Category
- [Radiation](https://sterigenics.com/white-paper-category/radiation/)
- [Ethylene Oxide](https://sterigenics.com/white-paper-category/ethylene-oxide/)

## Optional
- [Sitemap index](https://sterigenics.com/sitemap_index.xml)