Top Sites>Home - Sanford Burnham Prebys

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# Sanford Burnham Prebys

> Sanford Burnham Prebys is dedicated to pushing biomedical discoveries faster and further toward clinical treatment and therapies that improve human lives\.

Generated by Yoast SEO v27.2, this is an llms.txt file, meant for consumption by LLMs.

## Pages
- [Funding Opportunities](https://sbpdiscovery.org/support-us/funding-opportunities/)
- [Center for Data Science and Artificial Intelligence](https://sbpdiscovery.org/research/centers/center-for-data-science-and-artificial-intelligence/): Knowledge is data, derived from facts, information, and ideas\. The modern scientific enterprise is in the age of data science, utilizing rapidly advancing tools like computational biology, machine learning, and artificial intelligence\.
- [Philanthropy](https://sbpdiscovery.org/philanthropy/): Our researchers, faculty and trainees rely on people like you, who believe that advanced science will lead to new frontiers of human well being\. Through philanthropy, we translate science into health\.
- [Home](https://sbpdiscovery.org/)
- [Focus On Seminar Series](https://sbpdiscovery.org/research/centers/nci-designated-cancer-center/seminar/): Exploring Major Topics in Cancer Research\. We're Highlighting the Current Leaders in their Fields of Study

## Posts
- [Sanford Burnham Prebys goes Inside the Science of Heart Disease](https://sbpdiscovery.org/sanford-burnham-prebys-goes-inside-the-science-of-heart-disease/): Event recording now available for panel discussion with scientists held on April 15, 2026\.
- [Q \& A with Postdoctoral Researcher Nilofer Sayed, PhD, from the Dhar Lab](https://sbpdiscovery.org/q-a-with-postdoctoral-researcher-nilofer-sayed-phd-from-the-dhar-lab/): At Sanford Burnham Prebys, postdoctoral researcher Nilofer Sayed, PhD, a postdoctoral researcher in the lab of Debanjan Dhar, PhD, studies the progression of fatty liver disease to cirrhosis and hepatocellular carcinoma to identify new potential treatments that could reverse or halt disease advancement\.
- [Science in Pictures](https://sbpdiscovery.org/science-in-pictures-apr-20-26/): A weekly image series featuring selected pictures in science • Zebrafish neural tube
- [Science in Pictures](https://sbpdiscovery.org/science-in-pictures-apr-13-26/): A weekly image series featuring selected pictures in science • Vibrio bacteria
- [Science in Pictures](https://sbpdiscovery.org/science-in-pictures-apr6-26/): A weekly image series featuring selected pictures in science • Blood clot

## Scientists
- [Gregg Duester, PhD](https://sbpdiscovery.org/scientists/gregg-duester-phd/)
- [Hudson Freeze, PhD](https://sbpdiscovery.org/scientists/hudson-freeze-phd/)
- [Su\-Chun Zhang, MD, PhD](https://sbpdiscovery.org/scientists/su-chun-zhang-md-phd/)
- [Kristiina Vuori, MD, PhD](https://sbpdiscovery.org/scientists/kristiina-vuori-md-phd/)
- [Rolf Bodmer, PhD](https://sbpdiscovery.org/scientists/rolf-bodmer-phd/)

## Labs
- [Tharp Lab files](https://sbpdiscovery.org/labs/tharp-lab-files/): In the Tharp lab, we aim to understand how cells regulate and utilize metabolic programs to adapt to different microenvironments\. Our main goal is to develop therapeutics that prevent cancer cells from metastasizing \- by interfering with their ability to tune their metabolism to survive in secondary sites\.
- [Karin Lab](https://sbpdiscovery.org/labs/karin-lab/): In the Tharp lab, we aim to understand how cells regulate and utilize metabolic programs to adapt to different microenvironments\. Our main goal is to develop therapeutics that prevent cancer cells from metastasizing \- by interfering with their ability to tune their metabolism to survive in secondary sites\.
- [Tharp Lab](https://sbpdiscovery.org/labs/tharp-lab/): In the Tharp lab, we aim to understand how cells regulate and utilize metabolic programs to adapt to different microenvironments\. Our main goal is to develop therapeutics that prevent cancer cells from metastasizing \- by interfering with their ability to tune their metabolism to survive in secondary sites\.
- [Marth Lab](https://sbpdiscovery.org/labs/marth-lab/)
- [Bradley Lab](https://sbpdiscovery.org/labs/bradley-lab/): The Bradley Lab is focused on understanding the regulation of T lymphocytes in virus infections where the immune response results in viral clearance and the development of immunologic memory, and in chronic virus infections where the ongoing immune response leads to viral persistence and immune dysregulation\.

## Events
- [SBP\-SN Outreach Symposium »](https://sbpdiscovery.org/events/sbp-sn-outreach-symposium/): Join us for an inspiring evening where science meets community\! The Outreach Symposium gives postdocs and graduate students a platform to sharpen their science communication skills\.
- [Discovery Series: Inside the Science of Heart Disease »](https://sbpdiscovery.org/events/inside-the-science-of-heart-disease/): Our Discovery Series program offers a behind\-the\-scenes look at cardiovascular research at Sanford Burnham Prebys Medical Discovery Institute\. The presentation will explore how scientists are advancing the understanding of heart disease and translating discovery into potential therapies\.
- [Exploiting Pathogenic Traits to Target Therapeutics in Muscular Dystrophy »](https://sbpdiscovery.org/events/exploiting-pathogenic-traits-to-target-therapeutics-in-muscular-dystrophy/): Distinguished Cardiovascular and Muscular Diseases Seminar Series: Fabio Rossi, MD, The University of British Columbia
- [Focus On: Cancer Metabolism »](https://sbpdiscovery.org/events/focus-on-cancer-metabolism-muir/): Exploring major topics in cancer research\. Alexander Muir, PhD, University of Chicago: "Hangry cancer cells: metabolic stress and tumor biology"
- [Focus On: Cancer »](https://sbpdiscovery.org/events/focus-on-cancer-weiss/): Exploring major topics in cancer research\. William A\. Weiss MD, PhD, UC San Francisco: "Models and vulnerabilities for brain cancers"

## Leadership
- [Diane Klotz, PhD](https://sbpdiscovery.org/leadership/diane-klotz-phd/)
- [Tja Owens, BSc](https://sbpdiscovery.org/leadership/tja-owens-bsc/)
- [Kari La Com](https://sbpdiscovery.org/leadership/kari-la-com/)
- [Mike Afshar](https://sbpdiscovery.org/leadership/mike-afshar/)
- [Angelica Rocha, PhD](https://sbpdiscovery.org/leadership/angelica-rocha-phd/)

## Trustees
- [Stuart A\. Tanz](https://sbpdiscovery.org/trustees/stuart-a-tanz/)
- [David L\. Szekeres](https://sbpdiscovery.org/trustees/david-l-szekeres/)
- [Lonna J\. Williams Stolper](https://sbpdiscovery.org/trustees/lonna-j-williams-stolper/)
- [Ted Roth](https://sbpdiscovery.org/trustees/ted-roth/)
- [William A\. Roper](https://sbpdiscovery.org/trustees/william-a-roper/)

## Featured Articles
- [RNA isoform diversity, splicing variants and switching in single cells of the Alzheimer’s disease brain](https://sbpdiscovery.org/paper-of-the-week/rna-isoform-diversity-splicing-variants-and-switching-in-single-cells-of-the-alzheimers-disease-brain/)
- [Synthesis and Characterization of ULK1/2 Kinase Inhibitors That Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non\-Small Cell Lung Cancer](https://sbpdiscovery.org/paper-of-the-week/synthesis-and-characterization-of-ulk1-2-kinase-inhibitors-that-inhibit-autophagy-and-upregulate-expression-of-major-histocompatibility-complex-i-for-the-treatment-of-non-small-cell-lung-cancer/)
- [Tissue morphology predicts telomere shortening in human tissues](https://sbpdiscovery.org/paper-of-the-week/tissue-morphology-predicts-telomere-shortening-in-human-tissues/)
- [Smac mimetic combined with eCD4\-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques](https://sbpdiscovery.org/paper-of-the-week/smac-mimetic-combined-with-ecd4-ig-reverses-latency-without-reducing-shiv-reservoirs-in-rhesus-macaques/)
- [SAKURA: a knowledge\-guided approach to recovering important, rare signals from single\-cell data](https://sbpdiscovery.org/paper-of-the-week/sakura-a-knowledge-guided-approach-to-recovering-important-rare-signals-from-single-cell-data/)

## Press Releases
- [Sanford Burnham Prebys welcomes two new members to its board of directors](https://sbpdiscovery.org/press/sanford-burnham-prebys-welcomes-two-new-members-to-its-board-of-directors/): Sanford Burnham Prebys has added two new and distinguished members to its Board of Directors: Sheri L\. Jamieson and Neil Davis Wachsberger\.
- [Researchers identify new genetic disease that interferes with brain development](https://sbpdiscovery.org/press/researchers-identify-new-genetic-disease-that-interferes-with-brain-development/): Study from the Freeze lab finds that a mutation destabilizes proteins involved in how children grow and mature\.
- [Overcoming ovarian cancer’s resistance to immunotherapy](https://sbpdiscovery.org/press/overcoming-ovarian-cancers-resistance-to-immunotherapy/): A triple combination therapy’s preclinical results and how blocking a protein mobilizes an anti\-tumor immune response\.
- [Computational model measures key aging metric from routine biopsies](https://sbpdiscovery.org/press/computational-model-measures-key-aging-metric-from-routine-biopsies/): Study from the Sinha lab demonstrates a new method for quickly and cheaply predicting telomere length, enables larger experiments\.
- [New computational biology tool automates and standardizes genome sequencing analysis](https://sbpdiscovery.org/press/new-computational-biology-tool-automates-and-standardizes-genome-sequencing-analysis/): The open\-access metapipeline\-DNA resource makes analyzing large and complicated data more accessible\.

## Magazines
- [Summer 2011](https://sbpdiscovery.org/magazine/summer-2011/)
- [Winter 2006](https://sbpdiscovery.org/magazine/winter-2006-2/)
- [Spring 2007](https://sbpdiscovery.org/magazine/spring-2007-2/)
- [Winter 2011](https://sbpdiscovery.org/magazine/winter-2011/)
- [Fall 2003](https://sbpdiscovery.org/magazine/fall-2003/)

## Science 101 Articles
- [Science 101: Liver disease](https://sbpdiscovery.org/science-101/science-101-liver-disease/)
- [Science 101: Breast cancer](https://sbpdiscovery.org/science-101/science-101-breast-cancer/)
- [Science 101:  Muscle](https://sbpdiscovery.org/science-101/science-101-muscle/)
- [Science 101: Stem cells](https://sbpdiscovery.org/science-101/science-101-stem-cells/): Stem cells are the earliest type of cell, found in both embryonic and adult organisms\. Through differentiation, they can become virtually any type of cell in the human body\.
- [Science 101: Rare Diseases](https://sbpdiscovery.org/science-101/science-101-rare-diseases/)

## Categories
- [Uncategorized](https://sbpdiscovery.org/category/uncategorized/)
- [Research News](https://sbpdiscovery.org/category/researchnews/)
- [What's Happening](https://sbpdiscovery.org/category/whatshappening/)
- [People](https://sbpdiscovery.org/category/people/)
- [Workforce Engagement and Belonging](https://sbpdiscovery.org/category/workforce-engagement-belonging/)

## Tags
- [Cancer Center](https://sbpdiscovery.org/tag/cancercenter/)
- [NIH funding](https://sbpdiscovery.org/tag/nihfunding/)
- [cancer](https://sbpdiscovery.org/tag/cancer/)
- [grants](https://sbpdiscovery.org/tag/grants/)
- [Science in Pictures](https://sbpdiscovery.org/tag/scienceinpictures/)

## Faculty Types
- [Faculty](https://sbpdiscovery.org/faculty-type/faculty/)
- [Staff](https://sbpdiscovery.org/faculty-type/staff/)
- [Emeritus Faculty](https://sbpdiscovery.org/faculty-type/emeritus-faculty/)
- [Research Faculty](https://sbpdiscovery.org/faculty-type/research-faculty/)
- [Adjunct Faculty](https://sbpdiscovery.org/faculty-type/adjunct-faculty/)

##  Positions
- [Member](https://sbpdiscovery.org/scientist-position/member/)
- [Professor](https://sbpdiscovery.org/scientist-position/professor/)
- [Assistant Professor](https://sbpdiscovery.org/scientist-position/assistant-professor/)
- [Director](https://sbpdiscovery.org/scientist-position/director/)
- [Associate Professor](https://sbpdiscovery.org/scientist-position/associate-professor/)

## Related Diseases
- [Cancer](https://sbpdiscovery.org/related-diseases/cancer/)
- [Breast Cancer](https://sbpdiscovery.org/related-diseases/breast-cancer/)
- [Alzheimer's Disease](https://sbpdiscovery.org/related-diseases/alzheimers-disease/)
- [Aging\-Related Diseases](https://sbpdiscovery.org/related-diseases/aging-related-diseases/)
- [Neurodegenerative and Neuromuscular Diseases](https://sbpdiscovery.org/related-diseases/neurodegenerative-and-neuromuscular-diseases/)

## Phenomena or Processes
- [Cell Signaling](https://sbpdiscovery.org/phenomena-processes/cell-signaling/)
- [Cell Biology](https://sbpdiscovery.org/phenomena-processes/cell-biology/)
- [Inflammation](https://sbpdiscovery.org/phenomena-processes/inflammation/)
- [Aging](https://sbpdiscovery.org/phenomena-processes/aging/)
- [Cancer Biology](https://sbpdiscovery.org/phenomena-processes/cancer-biology/)

## Anatomical Systems and Sites
- [Immune System and Inflammation](https://sbpdiscovery.org/anatomical-system-site/immune-system-and-inflammation/)
- [Brain](https://sbpdiscovery.org/anatomical-system-site/brain/)
- [General Cell Biology](https://sbpdiscovery.org/anatomical-system-site/general-cell-biology/)
- [Nervous System](https://sbpdiscovery.org/anatomical-system-site/nervous-system/)
- [Vasculature](https://sbpdiscovery.org/anatomical-system-site/vasculature/)

## Research Models
- [Mouse](https://sbpdiscovery.org/research-models/mouse/)
- [Human Cell Lines](https://sbpdiscovery.org/research-models/human-cell-lines/)
- [Mouse Cell Lines](https://sbpdiscovery.org/research-models/mouse-cell-lines/)
- [Primary Human Cells](https://sbpdiscovery.org/research-models/primary-human-cells/)
- [Primary Cells](https://sbpdiscovery.org/research-models/primary-cells/)

## Techniques and Technologies
- [Cellular and Molecular Imaging](https://sbpdiscovery.org/techniques-technologies/cellular-and-molecular-imaging/)
- [Bioinformatics](https://sbpdiscovery.org/techniques-technologies/bioinformatics/)
- [Drug Discovery](https://sbpdiscovery.org/techniques-technologies/drug-discovery/)
- [Fluorescence Microscopy](https://sbpdiscovery.org/techniques-technologies/fluorescence-microscopy/)
- [Gene Expression](https://sbpdiscovery.org/techniques-technologies/gene-expression/)

## Leadership Types
- [Board of Directors](https://sbpdiscovery.org/leadership-type/board-of-directors/)
- [Administrative](https://sbpdiscovery.org/leadership-type/administrative/)
- [Scientific](https://sbpdiscovery.org/leadership-type/scientific/)
- [Management](https://sbpdiscovery.org/leadership-type/management/)
- [Scientific Advisory Board](https://sbpdiscovery.org/leadership-type/sab/)

## Page Types
- [Shared Resource](https://sbpdiscovery.org/page-type/shared-resource/)
- [Tribute](https://sbpdiscovery.org/page-type/tribute/)
- [Center](https://sbpdiscovery.org/page-type/center/)
- [Theme](https://sbpdiscovery.org/page-type/theme/)
- [Program](https://sbpdiscovery.org/page-type/program/)

## Event Types
- [Seminar](https://sbpdiscovery.org/event-type/seminar/)
- [Symposium](https://sbpdiscovery.org/event-type/symposium/)
- [Community Forum](https://sbpdiscovery.org/event-type/community-forum/)
- [Other](https://sbpdiscovery.org/event-type/other/)

## Event Categories
- [Cancer Center Seminar Series](https://sbpdiscovery.org/event-category/cancer-center-seminar-series/)
- [DEIB](https://sbpdiscovery.org/event-category/deib/)

## Optional
- [Sitemap index](https://sbpdiscovery.org/sitemap_index.xml)